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Toxicological information

Toxicity to reproduction

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Administrative data

Endpoint:
toxicity to reproduction
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
secondary source
Title:
Predicted Values-Estrogen Receptor Binding Affinity. Algorithm Version:v5.0.0.184
Author:
Predicted Values-Estrogen Receptor Binding Affinity. Algorithm Version:v5.0.0.184
Bibliographic source:
ACD/Labs (http://weblab.acdlabs.com)

Materials and methods

Test guideline
Guideline:
other:
Principles of method if other than guideline:
ACD/Labs Predicted Values-Estrogen Receptor Binding Affinity. Algorithm Version:v5.0.0.184

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Results: P0 (first parental generation)

Effect levels (P0)

Dose descriptor:
other:
Basis for effect level:
other: No binding to Estrogen Receptor Alpha (Log RBA <-3) for the sodium ethyl xanthate (CAS# 140-90-9),
Remarks on result:
not measured/tested
Remarks:
Effect level not specifiedGeneration not specified (migrated information)

Overall reproductive toxicity

Reproductive effects observed:
not specified

Any other information on results incl. tables

No binding to Estrogen Receptor Alpha (Log RBA <-3) for the following compounds:

- sodium ethyl xanthate (CAS# 140-90-9),

- sodium isopropyl xanthate (CAS# 140-93-2),

- sodium isobutyl xanthate (CAS# 25306-75-6)

Applicant's summary and conclusion

Conclusions:
No binding to Estrogen Receptor Alpha (Log RBA <-3) for the following compounds:- sodium ethyl xanthate (CAS# 140-90-9),- sodium isopropyl xanthate (CAS# 140-93-2),- sodium isobutyl xanthate (CAS# 25306-75-6)