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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

Waiving of experimental study. EC50 for algae was calculated to be ca. 26857 mg/L.

Key value for chemical safety assessment

Additional information

Data from a higher trophic level (fish) are available from 2 studies which show that aquatic toxicity does not occur. Aquatic toxicity also does not occur at the trophic level of invertebrates (Dahnia magna), for which 2 studies are available. In accordance with Annex XI No. 1.2 an experimental study is not conducted as there is sufficient weight of evidence from several independent sources of information leading to the assumption/conclusion that the substance does not cause aquatic toxicity to algae.

EC50 for algae was calculated to be ca. 26857 mg/L. Considering the fact that calculation models for aquatic toxicity to algae usually produce values which are conservative to unrealistic conservative, even the estimated high EC50 might not reflect actual toxicity to algae by L-arginine. Higher EC50 might be possible.

L-arginine is a naturally occuring amino acid which is omnipresent bin nature. It is a basic metabolit and building block of all living organisms and cells and is also a nutrient for algae. Thus significant toxicity to algae can be excluded.