Registration Dossier
Registration Dossier
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EC number: 201-173-7 | CAS number: 79-06-1
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1980
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Handbook data
Data source
Reference
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- Fujisawa, S and Masuhara, E
- Year:
- 1 980
- Bibliographic source:
- J. Dent. Res. 59,|2056 - 2061
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- no
- Remarks:
- Pre-GLP
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Acrylamide
- EC Number:
- 201-173-7
- EC Name:
- Acrylamide
- Cas Number:
- 79-06-1
- Molecular formula:
- C3H5NO
- IUPAC Name:
- prop-2-enamide
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- -0.9
- Temp.:
- 20 °C
- pH:
- ca. 7
Applicant's summary and conclusion
- Conclusions:
- Acrylamide has a very low octanol/water partition coefficient. The log Pow is -0.9.
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