Registration Dossier
Registration Dossier
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EC number: 410-660-5 | CAS number: 1072830-14-8
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
It has not been possible to determine reliable details of possible metabolic routes as no adverse effects have been noted from testing performed on similar substances. An assessment can be made using data available on the degradation products.
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
Additional information
If swallowed, the substance will quickly hydrolyse to titanium dioxide, triisopropanolamine, propan-2-ol and propylene glycol. None of these substances are classified as hazardous and although some pH effects from contact with the amine may result in local irritation, this has not been reported from testing.
The substance is a viscous liquid with minimal risk of inhalation. If on contact with skin, it is likely that there will be exposure to the degradation products; none of these are considered harmful to the skin.
From public documents, the organic degradation products will themselves be readily metabolised if ingested and there is little evidence that the titanium dioxide will be absorbed.
For the IUCLD endpoints, a read-across titanate has been cited for some of the endpoints, but other references have also been added.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
