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EC number: 206-839-0 | CAS number: 381-73-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
Additional information
Appearance:
On the basis of physical observation and using the sense of smell Difluoroacetic acid was found to be an organic Pale yellow color liquid having ammonia like odor.
Melting point:
The freezing point of the compound Difluoroacetic acid is estimated to be -30.94 deg C.
Boling point:
Boiling Point of Difluoroacetic acid by distillation method was found to be 131 deg C at 970 hPa atmospheric pressure. There was no decomposition of the substance. Similar results have also been obtained from estimation studies as well.
Particle size
Granulometry (particle size distribution is a property that is relevant only to solids. Since Difluoroacetic acid is a liquid substance and shall be used in non-solid form, this end point was considered for waiver.
Density
The bulk density of Difluoroacetic acid by the mass by volume method was found to be1.467g/cm3 at room temperature of 37 deg C. The results have also been observed to be similar from estimation study report. The end point value is equivalent to 1467 kg/m3 at 37 deg C and thus as 20 deg C the value was corrected to 1478.59 kg/m3.
Vapour Pressure:
The equilibrium vapor pressure is an indication of a liquid's evaporation rate. It relates to the tendency of particles to escape from the liquid. A substance with a high vapor pressure at normal temperatures is often referred to asvolatile. As a general trend, vapor pressures of liquids at ambient temperatures increase with decreasing boiling points. Thus based on the estimations it was observed that the target substance have avapour pressure of to be 1170 Pa, which can be considered to be is a higher range slightly.
Partition co-efficient:
The experimental value of octanol water partition co-efficient (log Pow) of Difluoroacetic acid by Shake flask method was found to be 0.60097 at temperature 37 deg C and pH of 2.03.This value indicates that Difluoroacetic acid is hydrophilic in nature.
Solubility or organic solvents:
The experimental value of solubility of Difluoroacetic acid in methanol at temperature of 37deg C was found to be 1000000 mg/L indicating Difluoroacetic acid is very soluble in methanol. Also, the experimental value of solubility of Difluoroacetic acid in Petroleum ether at temperature of 37deg C was found to be 8000 mg/L indicating Difluoroacetic acid is soluble in Petroleum ether.
Surface tension:
The surface tension of the compound difluoroacetic acid was estimated to be 24.4099998474121 mN/m.
Flammability:
From the experimental values of flammability, Difluoroacetic acid ignited when the flame of Bunsen burner having temperature of 950 deg C was brought in contact with it. Thus it can be concluded that Difluoroacetic acid is flammable only at high temperature of about 950 deg C. However since such high temperatures are not found under normal circumstances of transportation and use, Difluoroacetic acid was considered non-flammable for chemical safety assessment.
Auto – flammability :
Difluoroacetic acid did not catch fire on being exposed to air at room temperature of 37 deg C and atmospheric pressure of 970 hPa. This indicates Difluoroacetic acid is not auto-flammable.
Flash point :
The flash point for Difluoroacetic acid by open cup method was found to be 61 Deg C at 970 hPa atmospheric pressure. Based on this information it can be infered that the substance is not flammable in nature.
Explosive :
According to theoretical considerations based on chemical structure, Difluoroacetic acid does not possess explosive properties. The reason for this is there are no chemical groups associated with explosive properties in Difluoroacetic acid. Thus, as per column 2 of Annex VII this end point was considered for waiver.
Oxidising properties :
Difluoroacetic acid was found to be mild oxidising since59.34ml of KMnO4 was required for getting the end point of the redox titration for 100 g of Difluoroacetic acid. Based the same is not sufficient to classify the substance as oxidising in nature.
Stability of organic solvents:
Difluoroacetic acid was found to be stable in organic solvent dichloro methane and no degradation products were formed after 24 hours as evident from the GC-MS chromatogram obtained at 0 hours and that obtained after 24 hours.
Dissociation constant:
The experimental pKa value for Difluoroacetic acid was found to be 0.02546 (average pKa value) at 37deg C indicating that the chemical has dissociation properties.
Viscosity:
Viscosity of Difluoroacetic acid by Ostwald Viscometer at temperature of 37 deg C was found to be 10.83 mPa.s.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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