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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Endpoint summary

Administrative data

Description of key information

Additional information


On the basis of physical observation and using the sense of smell Difluoroacetic acid was found to be an organic Pale yellow color liquid having ammonia like odor.


Melting point:

The freezing point of the compound Difluoroacetic acid is estimated to be -30.94 deg C.

Boling point:

Boiling Point of Difluoroacetic acid by distillation method was found to be 131 deg C at 970 hPa atmospheric pressure. There was no decomposition of the substance. Similar results have also been obtained from estimation studies as well.

Particle size

Granulometry (particle size distribution is a property that is relevant only to solids. Since Difluoroacetic acid is a liquid substance and shall be used in non-solid form, this end point was considered for waiver.


The bulk density of Difluoroacetic acid by the mass by volume method was found to be1.467g/cm3 at room temperature of 37 deg C. The results have also been observed to be similar from estimation study report. The end point value is equivalent to 1467 kg/m3 at 37 deg C and thus as 20 deg C the value was corrected to 1478.59 kg/m3.

Vapour Pressure:

The equilibrium vapor pressure is an indication of a liquid's evaporation rate. It relates to the tendency of particles to escape from the liquid. A substance with a high vapor pressure at normal temperatures is often referred to asvolatile. As a general trend, vapor pressures of liquids at ambient temperatures increase with decreasing boiling points. Thus based on the estimations it was observed that the target substance have avapour pressure of to be 1170 Pa, which can be considered to be is a higher range slightly. 

Partition co-efficient:

The experimental value of octanol water partition co-efficient (log Pow) of Difluoroacetic acid by Shake flask method was found to be 0.60097 at temperature 37 deg C and pH of 2.03.This value indicates that Difluoroacetic acid is hydrophilic in nature.

Solubility or organic solvents:

The experimental value of solubility of Difluoroacetic acid in methanol at temperature of 37deg C was found to be 1000000 mg/L indicating Difluoroacetic acid is very soluble in methanol. Also, the experimental value of solubility of Difluoroacetic acid in Petroleum ether at temperature of 37deg C was found to be 8000 mg/L indicating Difluoroacetic acid is soluble in Petroleum ether.

Surface tension:

The surface tension of the compound difluoroacetic acid was estimated to be 24.4099998474121 mN/m.


From the experimental values of flammability, Difluoroacetic acid ignited when the flame of Bunsen burner having temperature of 950 deg C was brought in contact with it. Thus it can be concluded that Difluoroacetic acid is flammable only at high temperature of about 950 deg C. However since such high temperatures are not found under normal circumstances of transportation and use, Difluoroacetic acid was considered non-flammable for chemical safety assessment.

Auto – flammability :

Difluoroacetic acid did not catch fire on being exposed to air at room temperature of 37 deg C and atmospheric pressure of 970 hPa. This indicates Difluoroacetic acid is not auto-flammable.

Flash point :

The flash point for Difluoroacetic acid by open cup method was found to be 61 Deg C at 970 hPa atmospheric pressure. Based on this information it can be infered that the substance is not flammable in nature.

Explosive :

According to theoretical considerations based on chemical structure, Difluoroacetic acid does not possess explosive properties. The reason for this is there are no chemical groups associated with explosive properties in Difluoroacetic acid. Thus, as per column 2 of Annex VII this end point was considered for waiver.

Oxidising properties :

Difluoroacetic acid was found to be mild oxidising since59.34ml of KMnO4 was required for getting the end point of the redox titration for 100 g of Difluoroacetic acid. Based the same is not sufficient to classify the substance as oxidising in nature.

Stability of organic solvents:

Difluoroacetic acid was found to be stable in organic solvent dichloro methane and no degradation products were formed after 24 hours as evident from the GC-MS chromatogram obtained at 0 hours and that obtained after 24 hours.

Dissociation constant:

The experimental pKa value for Difluoroacetic acid was found to be 0.02546 (average pKa value) at 37deg C indicating that the chemical has dissociation properties.


Viscosity of Difluoroacetic acid by Ostwald Viscometer at temperature of 37 deg C was found to be 10.83 mPa.s.