Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB

Classification of difluoroacetic acid for effects in the environment

In determining the classification appropriate to difluoroacetic acid, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below. 




Reliable studies are available to demonstrate that difluoroacetic acid is non persistent in the water environment. Moreover, its persistent characteristics are only observe in the sediment and soil compartment but exposure to the soil and sediment is generally unlikely and hence it has been concluded that difluoroacetic acid is non persistent in nature.  


Thus, difluoroacetic acid is classified as a non persistent (P) chemical. 


Potential to accumulate

The estimated log Kow values for difluoroacetic acid is less than 4 (Log Kow = 0.600). The potential for difluoroacetic acid to bioaccumulate in the tissues of organisms that inhabit aquatic or terrestrial matrices is negligible as the BCF factor for the substance is less than 1000.  


The estimated BCF of difluoroacetic acid is highest 3.2 dimensionless and below the threshold of 2000. 


Thus, difluoroacetic acid does not satisfy the criterion for classification as bioaccumulative (B).


The toxicity values of fish, invertebrates and algae are LC50 = 121.88 mg/L, LC50 = 236 mg/L and EC50 = 4141.5 mg/L, respectively. These values suggest classification for aquatic toxicity will not be applicable for all of the tropic levels and the same is based on the above mentioned estimation studies.


So,difluoroacetic acid does not satisfy the environmental effects criterion for classification as toxic (T).


Thus it can be inferred that difluoroacetic acid is a non PBT (including vPvB) substance.