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Long-term toxicity to aquatic invertebrates

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Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
Data is from ECOSAR version 1.11
Qualifier:
according to guideline
Guideline:
other: Modeling database
Principles of method if other than guideline:
ECOSAR v1.1
GLP compliance:
no
Specific details on test material used for the study:
-Name of the test material : Difluoroacetic acid
-Molecular formula : C2H2F2O2
-Molecular weight : 96.03 g/mol
-Substance type : Organic
Test organisms (species):
Daphnia magna
Test type:
not specified
Water media type:
not specified
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
1 628.246 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
immobilisation
Remarks on result:
other: ECOSAR v1.11
Validity criteria fulfilled:
not specified
Conclusions:
On the basis of effects observed in a static freshwater system, the NOEC value for the substance is estimated to be 1628.246 mg/l for aquatic invertebrate for 21 days of exposure duration.
Executive summary:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the test substance is estimated to be 1628.246 mg/l for aquatic invertebrate for 21 days of exposure duration.Since, the test substance is readily biodegradable , it can be concluded that the test chemical can be considered as non-toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.

Description of key information

Long term toxicity to aquatic invertebrate:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the test substance is estimated to be1628.246mg/l for aquatic invertebrate for 21 days of exposure duration.Since, the test substance is readily biodegradable , it can be concluded that the test chemical can be considered as non-toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.

Key value for chemical safety assessment

Additional information

Long term toxicity to aquatic invertebrate:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the test substance is estimated to be1628.246mg/l for aquatic invertebrate for 21 days of exposure duration.Since, the test substance is readily biodegradable , it can be concluded that the test chemical can be considered as non-toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.