Difluoroacetic acid

Long-term toxicity to aquatic invertebrates

Link to relevant study record(s)

Reference

Endpoint:

long-term toxicity to aquatic invertebrates

Type of information:

calculation (if not (Q)SAR)

Remarks:

Migrated phrase: estimated by calculation

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Justification for type of information:

Data is from ECOSAR version 1.11

Qualifier:

according to guideline

Guideline:

other: Modeling database

Principles of method if other than guideline:

ECOSAR v1.1

GLP compliance:

no

Specific details on test material used for the study:

-Name of the test material : Difluoroacetic acid
-Molecular formula : C2H2F2O2
-Molecular weight : 96.03 g/mol
-Substance type : Organic

Test organisms (species):

Daphnia magna

Test type:

not specified

Water media type:

not specified

Duration:

21 d

Dose descriptor:

NOEC

Effect conc.:

1 628.246 mg/L

Nominal / measured:

estimated

Conc. based on:

test mat.

Basis for effect:

immobilisation

Remarks on result:

other: ECOSAR v1.11

Validity criteria fulfilled:

not specified

Conclusions:

On the basis of effects observed in a static freshwater system, the NOEC value for the substance is estimated to be 1628.246 mg/l for aquatic invertebrate for 21 days of exposure duration.

Executive summary:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the test substance is estimated to be 1628.246 mg/l for aquatic invertebrate for 21 days of exposure duration.Since, the test substance is readily biodegradable , it can be concluded that the test chemical can be considered as non-toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.

Description of key information

Long term toxicity to aquatic invertebrate:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the test substance is estimated to be1628.246mg/l for aquatic invertebrate for 21 days of exposure duration.Since, the test substance is readily biodegradable , it can be concluded that the test chemical can be considered as non-toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.

Additional information

Long term toxicity to aquatic invertebrate:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the test substance is estimated to be1628.246mg/l for aquatic invertebrate for 21 days of exposure duration.Since, the test substance is readily biodegradable , it can be concluded that the test chemical can be considered as non-toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.