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Dissociation constant

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Description of key information

10.32 at 25 °C

Key value for chemical safety assessment

pKa at 20°C:

Additional information

A literature review was conducted. In a weight of evidence approach the literature values were evaluated. The REAXYS database (Adams et al.1942) reports the dissociation constant to be pKa = 10.46 at 25 °C. In addition the SRC PhysProp Database (Perrin 1965) reports the dissociation constant to be pKa = 10.32 at 25 °C. All values are in the same range and were therefore regarded as reliable. The pKa of 10.32 was chosen as key value for risk assessment as it was from the most reliable literature source according to ECHA IR/CSA chapter R7.a dated Nov 2012.