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EC number: 231-810-4 | CAS number: 7747-35-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
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- Flash point
- Auto flammability
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- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
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- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
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- Nanomaterial surface chemistry
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- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No study on the long-term effects of EDHO to fish is available.
Key value for chemical safety assessment
Additional information
EDHOis rapidly hydrolyzed to AEPD and formaldehyde, with half-lives of less than 4 hours at pH 4, 7, and 9 at 25 ºC. As a result of rapid hydrolysis and low potential for continuous input in the aquatic environment based on use patterns, potential for chronic exposure to EDHO is expected to be low. Bioaccumulation potential is expected to be minimal based on a reported log Kow of -0.32.
In addition, acute testing clearly indicated that fish were the least sensitive of the three trophic levels to EDHO exposure. The fish acute values ranged from 130 to 244 mg/L while the aquatic invertebrate acute values ranged from 16.9 to 138 mg/L and the algal acute values ranged from 1.08 to 2.09 mg/L. Chronic values were determined for algal species and the most sensitive invertebrate (Daphnia magna). The NOEC for the daphnid chronic study was determined to be 5 mg/L, an order of magnitude greater than the most sensitive trophic level (ErC50 for freshwater green alga of 0.513 mg/L. Since fish are vertebrates as well as the least acutely sensitive trophic level, it was neither scientifically nor ethically justified to determine a chronic value.
According to REACH Annex IX requirements, long-term toxicity testing shall only be considered when the chemical safety assessment indicates the need for further investigations. Hence, long-term testing can be waived for EDHO.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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