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EC number: 202-430-6 | CAS number: 95-54-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in soil
Administrative data
- Endpoint:
- biodegradation in soil: simulation testing
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Despite no guideline being available in 1966, methods are reproducible and straightforward, and results are reasonable.
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 966
- Report date:
- 1966
Materials and methods
- Principles of method if other than guideline:
- Test solution contained substituted benzenes as the sole carbon source. Inoculum was Niagara silt loam. Absorbancy of the centrifuged supernatant aliquot was monitored up to 64 days to monitor cleavage of benzene ring (cleavage results in loss of UV absorbancy).
- GLP compliance:
- no
- Test type:
- laboratory
Test material
- Reference substance name:
- o-phenylenediamine
- EC Number:
- 202-430-6
- EC Name:
- o-phenylenediamine
- Cas Number:
- 95-54-5
- Molecular formula:
- C6H8N2
- IUPAC Name:
- benzene-1,2-diamine
- Details on test material:
- No details provided in the publication.
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Soil classification:
- other: Niagara silt loam
Results and discussion
Half-life / dissipation time of parent compound
- Remarks on result:
- other: Neither of the phenylenediamine isomers (ortho and meta) exhibited ring cleavage within 64 days.
Any other information on results incl. tables
Neither of the phenylenediamine isomers (ortho and meta) exhibited ring cleavage within 64 days.
Most of the substituted anilines were not suitable substrates under the test conditions. The resistance of the anilines was rather surprising because amino compounds are universal cellular constituents, by contrast with nitro, chloro, and sulfonate compounds. Seven of the 15 anisoles were also largely inert when exposed to the mixed soil population, but six of the seven contained either a nitro or an amino substituent.
Applicant's summary and conclusion
- Conclusions:
- Neither of the phenylenediamine isomers (ortho and meta) exhibited ring cleavage within 64 days.
- Executive summary:
The rate of degradation of mono- and disubstituted benzenes (approx. 80 substances) by soil microorganisms was determined by a spectrophotometric technique. Chloro, sulfonate, and nitro groups retarded the rate of biodegradation whereas carboxyl and phenolic hydroxyl groups favored decomposition of the substituted benzenes. The meta isomer was commonly the most resistant to attack by soil microorganisms, but the ortho isomer was the most resistant for certain classes of compounds.
The loss of UV absorbancy was not observed over the 64 day period for ortho and meta phenylenediamine indicating slow decomposition under test conditions.
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