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EC number: 202-430-6 | CAS number: 95-54-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Additional information on environmental fate and behaviour
Administrative data
- Endpoint:
- additional information on environmental fate and behaviour
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- Although not conducted according to an accepted guideline, this study followed written procedures with minor variations. Water levels were not maintained throughout the first experiment so a second experiment was run using deionised make-up water. The second experiment was not run in duplicate and did not have a water control.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 985
- Report date:
- 1985
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The half-life of the test substance was determined in Haskell Laboratory well water under static aerated conditions at 25ºC. Measurements of the loss from solution was made by paired-ion reverse phase HPLC.
- GLP compliance:
- yes
Test material
- Reference substance name:
- o-phenylenediamine
- EC Number:
- 202-430-6
- EC Name:
- o-phenylenediamine
- Cas Number:
- 95-54-5
- Molecular formula:
- C6H8N2
- IUPAC Name:
- benzene-1,2-diamine
- Details on test material:
- Purity: 99.5%
Constituent 1
Results and discussion
Any other information on results incl. tables
The concentrations of test substance measured in experiments 1 and 2 are shown in the table below. Day 21, experiment 1, values were analysed but the results were not reported because of unknown materials interfering with the HPLC analysis.
Concentrations (mg/L) of Remaining Test Substance
Time |
Exp 1, 2.5 mg/L (Initial Conc.) |
Exp 2, 2.5 mg/L (Initial Conc.) |
Exp 1, 25 mg/L (Initial Conc.) |
Exp 2, 25 mg/L (Initial Conc.) |
0-hour |
2.4 |
2.2 |
22.7 |
22.4 |
1 day |
2.1 |
1.9 |
18.9 |
22.2 |
2 day |
1.6 |
1.4 |
14.4 |
16.5 |
4 day |
1 |
0.82 |
7.9 |
13 |
7 day |
0.42 |
0.3 |
3 |
7 |
14 day |
nq |
nq |
0.66 |
1.1 |
21 day |
z |
nm |
z |
nm |
nm: not measured, nq: not quantifiable, z: analyzed but not reported, unkown materials in samples interfered with the analysis
The test substance was lost from solution in both experiments and at both concentrations. The loss from solution may not be due totally to oxidative processes since low levels of microorganisms were detected which may have played a small role in the degradation.
Physical-chemical measurements were taken for the H2O controls in each experiment. In experiment 1, nearly 80% of the initial volume was lost at the end of the 21-day test period. The alkalinity, hardness, and conductivity increases in experiment 1 are probably due to evaporation which concentrated these inorganic constituents. While not measured in the test substance solutions, the evidence indicates that these increases occurred in the test solutions as well. In experiment 2, the volume of solution was held constant by addition of deionised water which prevented these constituents from concentrating.
The statistical analysis is described in detail within the report. The data from experiment 2 was used. The regression lines that best fit the data were chosen for estimating the half-lives for the test substance. The loss of test material generally followed first order kinetics.
-
Applicant's summary and conclusion
- Conclusions:
- The shortest oxidative half-lives were those of PPD (4.1 hours at 2.5 mg/L , k = 0.17/hr; 8.9 hours at 25 mg/L , k = 0.08/hr), followed by OPD (2.7 days at 2.5 mg/L, k = 0.26/day; 4.5 days at 25 mg/L, k = 0.16/day), and finally by MPD (13.4 days at 2.5 mg/L, k = 0.05/day; 33.6 days at. 25 mg/L, k = 0.02/day).
- Executive summary:
The half-lives of o-phenylenediamine (OPD), m-phenylenediamine (MPD), and p-phenylenediamine (PPD) were determined in Haskell Laboratory well water under static aerated conditions at 25ºC. Measurements of the loss of each isomer from solution were made by paired-ion reverse phase HPLC. The shortest oxidative half-lives were those of PPD, followed by OPD, and finally by MPD. The loss of test material generally followed first order kinetics.
Haskell well water was selected for this study because the aquatic toxicities of OPD, PPD and MPD were previously determined in the same water. The water is monitored on a yearly basis for priority pollutants, selected organic pesticides, and inorganic constituents. The organic constituents are generally below the level of detection.
The study was conducted in two experiments. During the first experiment, which ran for 21 days, the volume of the test vessels decreased due to evaporation, leading to the possibility that some of the test substance solutions may have become concentrated. For this reason, a second experiment was implemented.
The conditions of the second experiment were identical to the first with several exceptions. There were no replicates and only one water control. The test vessel water levels were kept constant with deionised water. The study ran 14 days.
The oxidative half-life results were 2.7 days at 2.5 mg/L , k = 0.26/d and 4.5 days at 25 mg/L , k = 0.16/d.
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