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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

Dimethyl(propyl)amine is readily biodegradable (according to OECD criteria).

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable
Type of water:

Additional information

Target substance dimethyl(propyl)amine (CAS 926 -63 -6):

In a study, conducted according to OECD Guideline 310 the biodegradability of dimethyl(propyl)amine (CAS 926-63-6) was studied (BASF SE, 2012, report no. 27G0302/10G091). In this GLP-study municipal activated sludge was used as inoculum. The degradation reached 78 ± 4% (CO2 evolution) after 28 days of exposure. The limit for ready biodegradability (>60%) was reached within the 10 days window. Therefore, the substance is considered to be readily biodegradable according to OECD criteria.


Source substance ethyldimethylamine (CAS 598-56-1):

Biodegradability of ethyldimethylamine was studied using the OECD method 301D (Gancet, 2009). Activated domestic sludge (non-adapted) was used as inoculum. Results show that the substance reached a maximum biodegradation level of 67 % in 28 days and this level was obtained within a 10 days window. Based on these criteria, ethyldimethylamine is readily biodegradable.

Note: the percentage of degradation of the reference item reached only a level of 31 % by 14 days which is below the requested level of 60 %. This can probably be explained by a inoculum activity which is not optimum. Nevertheless this does not invalidate the final result of the study. One can just expect that with a higher inoculum activity, biodegradation of ethyldimethylamine would have been even faster.


Source substance N,N-dimethylbutylamine (CAS 927-62-8):

N,N-dimethylbutylamine was tested to be readily biodegradable in a valid OECD 301B study. Activated sludge from a municipal sewage treatment plant was used as inoculum. Biodegradation of N,N-dimethylbutylamine was 73% after 28 days, and 61% at the end of the 10-day-window (CO2 evolution). N,N-dimethylbutylamine is considered to be readily biodegradable (LAUS, 2012).

For details see ECHA database: Search date: 2021-05-18