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Biodegradation in water: screening tests

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Description of key information

Dimethyl(propyl)amine is readily biodegradable (according to OECD criteria).

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable
Type of water:

Additional information

Target substance dimethyl(propyl)amine (CAS 926 -63 -6):

In a study, conducted according to OECD Guideline 310 the biodegradability of dimethyl(propyl)amine (CAS 926-63-6) was studied (BASF SE, 2012, report no. 27G0302/10G091). In this GLP-study municipal activated sludge was used as inoculum. The degradation reached 78 ± 4% (CO2 evolution) after 28 days of exposure. The limit for ready biodegradability (>60%) was reached within the 10 days window. Therefore, the substance is considered to be readily biodegradable according to OECD criteria.


Source substance ethyldimethylamine (CAS 598-56-1):

Biodegradability of ethyldimethylamine was studied using the OECD method 301D (Gancet, 2009). Activated domestic sludge (non-adapted) was used as inoculum. Results show that the substance reached a maximum biodegradation level of 67 % in 28 days and this level was obtained within a 10 days window. Based on these criteria, ethyldimethylamine is readily biodegradable.

Note: the percentage of degradation of the reference item reached only a level of 31 % by 14 days which is below the requested level of 60 %. This can probably be explained by a inoculum activity which is not optimum. Nevertheless this does not invalidate the final result of the study. One can just expect that with a higher inoculum activity, biodegradation of ethyldimethylamine would have been even faster.


Source substance N,N-dimethylbutylamine (CAS 927-62-8):

N,N-dimethylbutylamine was tested to be readily biodegradable in a valid OECD 301B study. Activated sludge from a municipal sewage treatment plant was used as inoculum. Biodegradation of N,N-dimethylbutylamine was 73% after 28 days, and 61% at the end of the 10-day-window (CO2 evolution). N,N-dimethylbutylamine is considered to be readily biodegradable (LAUS, 2012).

For details see ECHA database: Search date: 2021-05-18