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Short-term toxicity to fish

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CAS 926 -63 -6:


According to Regulation (EC) 1907/2006, Annex IX, Section 9.1.3, Column 2, the study on the short-term toxicity to fish does not need to be conducted if long-term aquatic toxicity study on fish is available. Based on ECHA decision number CCH-D-2114552926-38-01/D, the Registrant will perform long-term toxicity testing on fish, i.e. a study according to OECD TG 210 (Fish, Early-Life Stage Toxicity Test).


 


CAS 598 -56 -1:


In a study according to DIN 38412-15 on N,N-dimethyl-ethylamine (CAS 598-56-1) with non-buffered test solutions all fish died within 96 hours if exposed to test concentrations of 46.4 mg/L and above. However, as no mortality or adverse effects was observed in neutralised test solutions during the complete exposure period (96-h LC50 > 100 mg/L; BASF AG, 1980), it may be stated that the observed effects in non-neutralised test solutions are solely based on pH.


 


CAS 121 -44 -8:


There are further experimental data on the read-across substance triethylamine (CAS 121-44-8) from two studies according to OECD 203 (96-h LC50: 24 mg/L; MOE, 1999) and EPA OTS 797.1400 (96-h LC50: 36 mg/L; Machado, 1994).