Registration Dossier
Registration Dossier
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EC number: 446-630-3 | CAS number: 181587-01-9
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 1 µg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.003 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.1 µg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 100 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.45 µg/kg sediment dw
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.45 µg/kg sediment dw
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.001 mg/kg soil dw
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
Classification related key information
Biodegradation in water: screening test: Not readily biodegradable: 18% (ThCO2) in 28 days (OECD 301 B)
Log Kow: 2.9 (OECD 117)
BCF: 8.92 - 10.24 for Danio rerio (OECD 305 B)
Acute toxicity:
- to Fish: LC50 (96h) = 0.26 mg/L for Lepomis macrochirus (OECD 203)
- to Algae: ECr50 (72h) > 3 mg/L, for Pseudokirchneriella subcapitata (OECD 201)
- to aquatic invertebrates: EC50 (48h) = 2.24 mg/L for Chironomus riparius (OECD 235)
- to aquatic plants: IC50 (7 d) > 4.07 for Lemna gibba (OECD 221)
Chronic toxicity:
- to Fish: NOEC (35d) = 0.01 mg/L for Pimephales promelas (OECD 210)
- to Algae: NOEC (72h) = 0.375 mg/L for Scenedesmus subspicatus (OECD 201)
- to aquatic invertebrates: NOEC (21d) = 0.4 mg/L for Daphnia magna (EPA OPP 72-4)
- to aquatic plants: NOEC (7 d) = 0.039 mg/L for Lemna gibba (OECD 221)
Classification justification according to CLP
Based on the data above, the substance is considered not rapidly biodegradable. The acute aquatic toxicity LC50 is < 1 mg/L for Lepomis macrochirus. Valid chronic toxicity data are available for fish, algae and Daphnia – the lowest NOEC is < 0.1 mg/L for Pimephales promelas. Therefore, the substance needs to be classified and labelled as environmental hazard Acute Cat. 1 and Chronic Cat. 1 according to the consolidated version of Regulation (EC) No 1272/2008 and further amendments (ATPs).
M-factor for acute aquatic toxicity: 1
M-factor for chronic aquatic toxicity: 10
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