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Ecotoxicological information

Sediment toxicity

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Endpoint:
sediment toxicity: short-term
Type of information:
experimental study
Adequacy of study:
key study
Study period:
11/03/2005 - 21/03/2005
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP not known, guideline study, acceptable with restrictions
Justification for type of information:
A discussion and report on the read across strategy is given as an attachment in Section 13.
Cross-reference
Reason / purpose:
read-across: supporting information
Reference
Endpoint:
sediment toxicity: short-term
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Study period:
11/03/2005 - 21/03/2005
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP not known, guideline study, acceptable with restrictions
Justification for type of information:
A discussion and report on the read across strategy is given as an attachment in Section 13.
Reason / purpose:
read-across source
Qualifier:
according to
Guideline:
ASTM E1367 (10-day Static Sediment Toxicity Test (Media: Sediment-marine))
Version / remarks:
92
Deviations:
not specified
GLP compliance:
not specified
Specific details on test material used for the study:
Details on properties of test surrogate or analogue material (migrated information):
not applicable
Analytical monitoring:
no
Details on sampling:
not applicable
Vehicle:
no
Details on sediment and application:
not reported
Test organisms (species):
Leptocheirus plumulosus
Details on test organisms:
Source: cultured in natural sediment
Holding Conditions Prior to test: cultured and maintained in natural sediment acclimated to 20 ± 1 degrees C prior to test intitiation. Cultures fed during this time but not when test was initiated.
Study type:
laboratory study
Test type:
static
Water media type:
saltwater
Type of sediment:
artificial sediment
Limit test:
no
Duration:
10 d
Exposure phase:
total exposure duration
Post exposure observation period:
none
Hardness:
data not reported
Test temperature:
20 ± 1°C
pH:
data not reported
Dissolved oxygen:
data not reported
Salinity:
data not reported
Ammonia:
data not reported
Nominal and measured concentrations:
Replicates exposed to artificial sediment spiked with test substance at 5 different concentrations (150, 300, 600, 1200 and 2400 mg/kg dw) and negative controls. All treatments prepared and dispensed 18 to 24 hrs prior to intitiating test. Treatments kept in dedicated environmental chamber.
Details on test conditions:
aeration: yes
no of organisms per vessel: 20
no of replicates per concentration: 5 replicates
photoperiod: 14:10
Reference substance (positive control):
no
Duration:
10 d
Dose descriptor:
LC50
Effect conc.:
182 mg/kg sediment dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Details on results:
concurrent 10 day control survival was 96%
Reported statistics and error estimates:
Probit analysis
Validity criteria fulfilled:
not specified
Conclusions:
The 10 day LC50 was 182 mg/kg (dry weight sediment).
Executive summary:

This study followed a standard guideline. No detail on the composition of the sediment is reported, and analytical monitoring was not included. This result gives an indication of the levels of the test substance that may cause sediment toxicity.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005
Report Date:
2005

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
ASTM E1367 (10-day Static Sediment Toxicity Test (Media: Sediment-marine))
Version / remarks:
92
Deviations:
not specified
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
sample 25889-83 D
Specific details on test material used for the study:
Details on properties of test surrogate or analogue material (migrated information):
not applicable

Sampling and analysis

Analytical monitoring:
no
Details on sampling:
not applicable

Test substrate

Vehicle:
no
Details on sediment and application:
not reported

Test organisms

Test organisms (species):
Leptocheirus plumulosus
Details on test organisms:
Source: cultured in natural sediment
Holding Conditions Prior to test: cultured and maintained in natural sediment acclimated to 20 ± 1 degrees C prior to test intitiation. Cultures fed during this time but not when test was initiated.

Study design

Study type:
laboratory study
Test type:
static
Water media type:
saltwater
Type of sediment:
artificial sediment
Limit test:
no
Exposure duration
Duration:
10 d
Exposure phase:
total exposure duration
Post exposure observation period:
none

Test conditions

Hardness:
data not reported
Test temperature:
20 ± 1°C
pH:
data not reported
Dissolved oxygen:
data not reported
Salinity:
data not reported
Ammonia:
data not reported
Nominal and measured concentrations:
Replicates exposed to artificial sediment spiked with test substance at 5 different concentrations (150, 300, 600, 1200 and 2400 mg/kg dw) and negative controls. All treatments prepared and dispensed 18 to 24 hrs prior to intitiating test. Treatments kept in dedicated environmental chamber.
Details on test conditions:
aeration: yes
no of organisms per vessel: 20
no of replicates per concentration: 5 replicates
photoperiod: 14:10
Reference substance (positive control):
no

Results and discussion

Effect concentrations
Duration:
10 d
Dose descriptor:
LC50
Effect conc.:
182 mg/kg sediment dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Details on results:
concurrent 10 day control survival was 96%
Reported statistics and error estimates:
Probit analysis

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The 10 day LC50 was 182 mg/kg (dry weight sediment).
Executive summary:

This study followed a standard guideline. No detail on the composition of the sediment is reported, and analytical monitoring was not included. This result gives an indication of the levels of the test substance that may cause sediment toxicity.