Registration Dossier
Registration Dossier
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EC number: 203-874-3 | CAS number: 111-48-8
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
Data source
Reference
- Reference Type:
- publication
- Title:
- IPCS, International Programme on Chemical Safety, Poisons Information Monograph 980, Thiodiglycol
- Author:
- WHO
- Year:
- 2 001
- Bibliographic source:
- [http://www.inchem.org/documents/pims/chemical/pim980.htm]
Materials and methods
- Type of study / information:
- Type of experience: Human
Test material
- Reference substance name:
- Ethane-1,2-diol
- EC Number:
- 203-473-3
- EC Name:
- Ethane-1,2-diol
- Cas Number:
- 107-21-1
- Molecular formula:
- C2H6O2
- IUPAC Name:
- ethylene glycol
Constituent 1
Results and discussion
- Results:
- Based on the structural similarity to ethylene glycol, thiodiglycol may produce depression of the central nervous system, metabolic acidosis and renal failure in severe intoxication.
Applicant's summary and conclusion
- Conclusions:
- Thiodiglycol may produce depression of the central nervous system, metabolic acidosis and renal failure in severe intoxication.
- Executive summary:
Based on the structural similarity to ethylene glycol, thiodiglycol may produce depression of the central nervous system, metabolic acidosis and renal failure in severe intoxication.
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