Registration Dossier

Toxicological information

Genetic toxicity: in vivo

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Administrative data

Endpoint:
genetic toxicity in vivo
Remarks:
Type of genotoxicity: other: Review
Type of information:
other: comprehensive review
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
review article or handbook
Title:
Cyclohexylamine
Author:
German MAK Commission
Year:
2006
Bibliographic source:
MAK Value Documentation, Vol22 DFG; WILEY Verlag, Weinheim

Materials and methods

Principles of method if other than guideline:
Comprehensive evaluation on all available data
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Cyclohexylamine
EC Number:
203-629-0
EC Name:
Cyclohexylamine
Cas Number:
108-91-8
Molecular formula:
C6H13N
IUPAC Name:
cyclohexanamine

Results and discussion

Test results
Genotoxicity:
negative
Remarks:
“On the whole, no genotoxic potential worth mentioning can be attributed to cyclohexylamine”

Applicant's summary and conclusion