Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
biodegradation in soil: simulation testing
Data waiving:
exposure considerations
Justification for data waiving:
the study does not need to be conducted because direct and indirect exposure of soil is unlikely

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Fate of Methylenediphenyl Diisocyanate and Toluene Diisocyanate in the Aquatic Environment
Author:
Yoshikuni Yakabe, Karen M. Henderson, William C. Thompson, Denis Pemberton, Bernard Tury, and Robert E. Bailey,
Year:
1999
Bibliographic source:
Environmental Science & Technology 1999 33 (15), 2579-2583; DOI: 10.1021/es981350c
Reference Type:
publication
Title:
Isocyanates; Encyclopedia of Toxicology
Author:
R.W. Knapp
Year:
2014
Bibliographic source:
Philip Wexler, Encyclopedia of Toxicology (Third Edition), Academic Press, 2014, Pages 1112-1131, ISBN 9780123864550,

Materials and methods

Results and discussion

Transformation products:
not measured
Remarks:
Upon contact with water the diisocyanate groups react by forming amines and CO2. The amines formed react further with unreacted diisocyanate groups of the diisocyanate homopolymer resulting in oligo-and subsequently polyurea components.

Applicant's summary and conclusion