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Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: secondary source (insufficient documented)

Data source

Reference
Reference Type:
secondary source
Title:
Summary tables of biological tests
Author:
Anonymous
Year:
1957
Bibliographic source:
National Research Council Chemical-Biological Coordination Center, 9, 132, 1957, cited in NIOSH/RTECS

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Bis(2-ethylhexyl) hydrogen phosphate
EC Number:
206-056-4
EC Name:
Bis(2-ethylhexyl) hydrogen phosphate
Cas Number:
298-07-7
Molecular formula:
C16H35O4P
IUPAC Name:
bis(2-ethylhexyl) hydrogen phosphate
Details on test material:
Phosphoric acid, bis(2-ethylhexyl)ester

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
propylene glycol
Doses:
31.3, 62.5, 125, 250, 500 mg/kg bw
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
62.5 mg/kg bw
Based on:
not specified

Any other information on results incl. tables

dose mg/kg mortality

31.3                     0 %

62.5                     50%

125                     100%

250                     100%

500                     100%

Applicant's summary and conclusion

Executive summary:

LD50 of bis(2-ethylhexyl) hydrogen phosphate is 62.5 mg/kg (no further data)