Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 266-358-7 | CAS number: 66423-13-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
It has been demonstrated in mammals, plant and soil environments that hydrolysis of structural analoges - racemic Mecoprop isooctyl ester (MCPP IOE) and Mecoprop-P 2-ethylhexyl ester (MCPP-P 2-EHE) is rapid. Following this initial degradation step the studies available for Mecoprop-P acid (MCPP-P acid) predict the behaviour of the material in the environment.
The structure analog Mecoprop-P 2-ethylhexyl ester (MCPP-P 2-EHE) has been shown to degrade to the parent Mecoprop-P acid (MCPP-P acid) by a process of hydrolysis. In sterile buffered water this process is very slow, but in naturally occurring water, for example river water the hydrolysis is very rapid with a DT50 of approximately 4 hours. In practical situations the low solubility of Mecoprop-P n-octyl ester (<0.1 mg/l) will mean that the ester will bind to inorganic and organic matter and be released only very slowly as the reservoir of dissolved material is depleted due to hydrolysis. In practical terms this will limit the mobility of Mecoprop-P n-octyl ester in aquatic systems.
For the atmospheric oxidation the estimated half-life of Mecoprop-P n-octyl ester is 17.6 hours. Considering this result a potential for long-range transport of Mecoprop-P n-octyl ester itself is not given.
Mecoprop-P n-octyl ester is of very low water solubility and under the conditions of sterile buffer solution Mecoprop-P n-octyl ester is stable to hydrolysis at environmental temperatures and pH values. Data on structural analoges, racemic Mecoprop isooctyl ester (MCPP IOE) and Mecoprop-P 2-ethylhexyl ester (MCPP-P 2-EHE), showed that it is stable under sterile buffer but degrades rapidly in natural water due to hydrolysis forming Mecoprop-P acid (MCPP-P acid) with a DT50 of 4.34 hours, respectively. An investigation on Mecoprop-P acid (MCPP-P acid) showed no further degradation within 31 days depending on hydrolysis.
Mecoprop-P n-octyl ester is not readily biodegradable and not inherently biodegradable. However, the hydrolysis product Mecoprop-P acid (MCPP-P acid) is readily biodegradable with a degradation rate of 85 % within 28 days.
The estimated BCF of Mecoprop-P n-octyl ester was 487.6 L/kg. However, since Mecoprop-P n-octyl ester rapidly hydrolyses in natural water this is only of theoretical interest. Additionally the determined BCF of 5.5 and 3.0 (non-edible and whole fish) for the hydrolysis product Mecoprop-P acid (MCPP-P acid) showed no potential for bioaccumulation. Therefore, Mecoprop-P n-octyl ester is considered as not being bioaccumulative in the environment.
Mecoprop-P n-octyl ester hydrolyses rapidly in natural water. Therefore, the hydrolysis product Mecoprop-P acid (MCPP-P acid) was used for further assessment of Mecoprop-P n-octyl ester with respect to its potential for adsorption on soil.
Determined in 3 sandy soils the Koc of Mecoprop-P acid (MCPP-P acid) was in the range of 135 – 167 indicating that Mecoprop-P acid (MCPP-P acid) has a low sorption potential to soil and sediment, and a moderate migration potential to groundwater.
Mecoprop-P acid (MCPP-P acid), the hydrolysis product of Mecoprop-P n-octyl ester, is considered nonvolatile from the aqueous phase with a Henry’s Law constant of 5.74 E-05 Pa*m3/mol at 20°C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

EU Privacy Disclaimer
This website uses cookies to ensure you get the best experience on our websites.