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Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

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Administrative data

Endpoint:
toxicity to soil macroorganisms except arthropods: short-term
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
other information
Study period:
1989
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Reliable source.

Data source

Reference
Title:
The acute toxicity of U46 KV-Fluid (560 g/L of MCPP acid as dimethylamine salt) to Eisenia fetida
Author:
Adema & Roza
Year:
1989

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 207 (Earthworm, Acute Toxicity Tests)
Deviations:
not specified
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
66423-09-4
Cas Number:
66423-09-4
IUPAC Name:
66423-09-4
Constituent 2
Reference substance name:
Mecoprop-P dimethylamine salt
IUPAC Name:
Mecoprop-P dimethylamine salt
Constituent 3
Reference substance name:
MCPP-P DMA
IUPAC Name:
MCPP-P DMA
Constituent 4
Reference substance name:
R-(+)-2-(4-chloro-2-methylphenoxy)-propionic acid, dimethylamine salt
IUPAC Name:
R-(+)-2-(4-chloro-2-methylphenoxy)-propionic acid, dimethylamine salt
Details on test material:
Purity: not specified

Test organisms

Test organisms (species):
Eisenia fetida
Animal group:
annelids
Details on test organisms:
average weight at the beginning of the test 0.59 g +/- 0.13 g (n = 40)

Study design

Study type:
laboratory study
Substrate type:
artificial soil
Limit test:
no
Total exposure duration:
14 d

Test conditions

Test temperature:
21°C
pH:
5.7
Moisture:
50 - 55 % %
Nominal and measured concentrations:
nominal: 0, 10, 32, 100, 320 and 1000 mg a.i./kg soil

Results and discussion

Effect concentrationsopen allclose all
Duration:
14 d
Dose descriptor:
LC50
Effect conc.:
988 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
14 d
Dose descriptor:
NOEC
Effect conc.:
100 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality

Any other information on results incl. tables

For Mecoprop-P dimethylamine salt (MCPP-P DMA) the 14d-LC50 was calculated to be 1764 mg/kg dry soil, corresponding to 988 mg/kg dry soil for Mecoprop-P acid (MCPP-P acid).

Within 14 days of exposure, no worm died at 571 g test substance/kg soil corresponding to 320 mg/kg for Mecoprop-P acid (MCPP-P acid), but they were wetter than the worms of the control and very sluggish.

The NOEC was determined to be 179 mg/kg soil for Mecoprop-P dimethylamine salt (MCPP-P DMA) corresponding to 100 mg/kg soil for Mecoprop-P acid (MCPP-P acid).

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Remarks:
expected to be valid source
Conclusions:
For Mecoprop-P acid (MCPP-P acid), the hydrolysis product of Mecoprop-P n-octyl ester, a 14d-LC50 of 988 mg/kg dry soil and a 14d-NOEC of 100 mg/kg dry soil were determined on the earthworm Eisenia fetida.
Executive summary:

Mecoprop-P n-octyl ester hydrolyses rapidly in natural water. Therefore, the hydrolysis product Mecoprop-P acid (MCPP-P acid) was used for further assessment of Mecoprop-P n-octyl ester with respect to toxicity on terrestrial macroorganisms.

 

In a test system according to the OECD Guideline 207 for Mecoprop-P acid (MCPP-P acid) a 14d-LC50 of 988 mg/kg dry soil and a 14d-NOEC of 100 mg/kg dry soil was obseved on the earthworm Eisenia fetida.