Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 209-132-5 | CAS number: 556-61-6
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
The partition coefficient of Methyl isothiocyanate was estimated with EPISUITE software (KOWWIN v1.67). The log Kow value is 1.30.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.3
- at the temperature of:
- 20 °C
Additional information
Log Kow of Methyl isothiocyanate was experimentally estimated at 0.94. Nevertheless no data are given in order to challenge the validity of this result. As a consequence, Methyl isothiocyanate can be considered as potentially characterised by a low potential for bioaccumulation and adsorption. The estimated data of EPISUITE (chapter 4.7 (Partition coefficient) in the record "U.S. E.P.A. / K2 SS / Octanol-Water Partition coefficient") which is 1.30 reinforces this conclusion. The impact of errors on model predictions for a low log Kow value (<2) is usually less critical. Also, for very high log Kow values (>8) the measurement itself is generally difficult, and the environmental models are often less sensitive and predictive in this log Kow range. For this reason the value taken into account for the risk assessment is 1.3.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
