Registration Dossier
Registration Dossier
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EC number: 209-132-5 | CAS number: 556-61-6
Endpoint summary
Administrative data
Description of key information
Additional information
In accordance with Column 2 adaptation statement of REACH Annex VIII, information requirement section 9.3.1, the determination of adsorption coefficient based on the physicochemical properties the substance can be expected to have a low potential for adsorption. The octanol water partition coefficient of MITC was estimated at 1.9. Based on this value we can safely conclude that MITC is characterized by a low potential of adsorption.
The ready biodegradability of methyl isothiocyanate was evaluated in a study performed in accordance with OECD testing guideline 301 D and GLP requirements. The maximum level of biodegradation was 0 % in 28 days. Therefore, according to these results, methyl isothiocyanate is not considered as readily biodegradable.
Using conditions representative of the upper Sacramento River system, site of a metam-sodium spill, hydrolysis half-lives in a buffered system were determined to be 65 and 178 days at 25 and 0 deg C, respectively, and a pH of 7.0; results at pH 10 were 0.7 and 10 days at 25 and 9 deg C, respectively, and at pH 4, half-lives of 15 and 67 days at 25 and 0 deg C, respectively, were reported. Nevertheless, these data should be considered with care because little information is available in order to challenge the validity of the data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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