Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

In accordance with Column 2 adaptation statement of REACH Annex VIII, information requirement section 9.3.1, the determination of adsorption coefficient based on the physicochemical properties the substance can be expected to have a low potential for adsorption. The octanol water partition coefficient of MITC was estimated at 1.9. Based on this value we can safely conclude that MITC is characterized by a low potential of adsorption.

The ready biodegradability of methyl isothiocyanate was evaluated in a study performed in accordance with OECD testing guideline 301 D and GLP requirements. The maximum level of biodegradation was 0 % in 28 days. Therefore, according to these results, methyl isothiocyanate is not considered as readily biodegradable.

Using conditions representative of the upper Sacramento River system, site of a metam-sodium spill, hydrolysis half-lives in a buffered system were determined to be 65 and 178 days at 25 and 0 deg C, respectively, and a pH of 7.0; results at pH 10 were 0.7 and 10 days at 25 and 9 deg C, respectively, and at pH 4, half-lives of 15 and 67 days at 25 and 0 deg C, respectively, were reported. Nevertheless, these data should be considered with care because little information is available in order to challenge the validity of the data.