Registration Dossier
Registration Dossier
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EC number: 279-420-3 | CAS number: 80206-82-2
Endpoint summary
Administrative data
Description of key information
Additional information
Acute toxicity to fish
The Alcohols, C12-14, 14-16 and 16-18 multi-component substances did not exhibit acute effects at loading rates where the solubility of the component alcohols was exceeded.
A reliable 96 h LC50 value of 131.25 mg/L has been calculated for the effects of the Alcohols, C12-14, towards freshwater fish taxonomic group. Therefore the test substance has been predicted to be non toxic at the limit of solubility, so the LC50 is 0.525 mg/L. Predicted to be non-toxic at the limit of solubility. This result is above the LoS (limit of solubility), therefore the substance is non-toxic at the limit of LoS and LC50 is >LoS.
The water solubility of the Alcohols, C12-14 is 4.0 mg/l at 1000 mg/L loading rate at 25 deg C (experimental database).This is about 250 times the water solubility of the test substance.
A reliable 96 h LC50 value of 147.75 mg/L has been calculated for the effects of the test substance towards fish taxonomic group.Therefore the test substance has been predicted to be non toxic at the limit of solubility, so the LC50 is 0.591 mg/L. Predicted to be non-toxic at the limit of solubility.
This result signifies that the test substance is not expected to be toxic at the limit of solubility.This result is above the LoS (limit of solubility), therefore the substance is non-toxic at the limit of LoS and LC50 is >LoS.
The water solubility of the Alcohols, C12-14 is 4.0 mg/l at 1000 mg/L loading rate at 25 degC (experimental database). This is about 250 times the water solubility of the test substance.
A reliable 48 h LC50 >5000 mg/L has been determined for the effects of Alcohols, C12-14 on the mortality of the freshwater fish Leuciscus idus . However this result is above the LoS (limit of solubility), therefore the substance is non-toxic at the limit of LoS and LC50 is >LoS.
Acute toxicity to aquatic invertebrates
The ECOSAR QSAR model predicts that LC50 for fresh water species Daphnid would to be 0.446 mg/l .This result signifies that the test substance is not expected to be toxic at the limit of solubility.This result is above the LoS (limit of solubility), therefore the substance is non-toxic at the limit of LoS and LC50 is >LoS.This is about 250 times the water solubility of the test substance.
A reliable 48 h EC50 value of 111.5 mg/L has been calculated for the effects of the test substance towards Daphnia magna. Therefore the test substance has been predicted to be non toxic at the limit of solubility, so the EC50 is 0.446 mg/L.
The water solubility of the Alcohols, C12-14 is 4.0 mg/l at 1000 mg/L loading rate at 25 degC (experimental database). This is about 250 times the water solubility of the test substance.
Toxicity to algae
The data show the multi-component substances containing alcohols with carbon numbers in the ranges of C6-12 to C12-16 to be acutely toxic at concentrations of between 3.1 and 0.03-0.1 mg/L. At these concentrations all the components are likely to have been fully dissolved. For the C12-18 and C14-16 multi-component substances there was evidence of toxic effects in tests conducted on water-accommodated fractions prepared at loading rates that will have exceeded the solubility of some components.
A 96 h LC50 value of 0.704 mg/L has been calculated for the effects of the Alcohols, C12-14, on the mortality of the Algae group.
The data show the multi-component substances containing alcohols with carbon numbers in the ranges C12-16 to be acutely toxic at concentrations of between 0.03-0.1 mg/L. At these concentrations all the components are likely to have been fully dissolved.
This result signifies that the test substance is expected to be toxic.
A NOEC value of 0.427 mg/L has been calculated for the effects of the test substance on the mortality of the Algae group.
This result signifies that the test substance is expected to be toxic.
Summary of Acute Toxicity for Organism Group andAquatic algae, cyanobacteriaand aquatic plants |
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Organism Group |
Average Acute Toxicity |
Acute |
Invertebrates |
Slightly toxic
|
Slightly toxic to Moderately toxic
|
Fish |
Not Acutely Toxic |
Not Acutely Toxicto Not Acutely Toxic |
Molluscs and Amphibians
|
Not Acutely Toxic
|
Not Acutely Toxic to Slightly toxic
|
Annelida and microorganisms
|
Not Acutely Toxic
|
Not Acutely Toxic to Not Acutely Toxic |
Aquatic algae, cyanobacteria and aquatic plants |
Highly toxic
|
Highly toxic to Moderately toxic
|
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