Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 279-420-3 | CAS number: 80206-82-2
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- other: published data
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Interlaboratory evaluation of a human patch test for the identification of skin irritation potential/hazard.
- Author:
- Griffiths H A, Wilhelm K P, Robinson M K, Wang X M, McFadden J, York M, Basketter D A
- Year:
- 1 997
- Bibliographic source:
- Food and Chemical Toxicology 35: 255-260
Materials and methods
- Type of study / information:
- Type: other: human skin irritation
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- inter-laboratory assessment of the human patch testb using a Hill Top chamber
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Hexan-1-ol
- EC Number:
- 203-852-3
- EC Name:
- Hexan-1-ol
- Cas Number:
- 111-27-3
- IUPAC Name:
- hexan-1-ol
- Details on test material:
- - Analytical purity: not givenEC Name hexan-1-olCAS Name 1-HexanolCAS Number 111-27-3EC Number 203-852-3Molecular Formula C6H14O
Constituent 1
Results and discussion
Any other information on results incl. tables
In this inter-laboratory assessment of the human patch test hexanol gave responses significantly lower than the positive control and results were
similar between laboratories. N-hexanol was therefore not considered as a skin irritant.
Applicant's summary and conclusion
- Conclusions:
- In this inter-laboratory assessment of the human patch test hexanol gave responses significantly lower than the positive control and results were
similar between laboratories. N-hexanol was therefore not considered as a skin irritant.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
