Registration Dossier
Registration Dossier
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EC number: 279-420-3 | CAS number: 80206-82-2
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- other: published data
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Interlaboratory evaluation of a human patch test for the identification of skin irritation potential/hazard.
- Author:
- Griffiths H A, Wilhelm K P, Robinson M K, Wang X M, McFadden J, York M, Basketter D A
- Year:
- 1 997
- Bibliographic source:
- Food and Chemical Toxicology 35: 255-260
Materials and methods
- Type of study / information:
- Type: other: human skin irritation
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- inter-laboratory assessment of the human patch testb using a Hill Top chamber
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Hexan-1-ol
- EC Number:
- 203-852-3
- EC Name:
- Hexan-1-ol
- Cas Number:
- 111-27-3
- IUPAC Name:
- hexan-1-ol
- Details on test material:
- - Analytical purity: not givenEC Name hexan-1-olCAS Name 1-HexanolCAS Number 111-27-3EC Number 203-852-3Molecular Formula C6H14O
Constituent 1
Results and discussion
Any other information on results incl. tables
In this inter-laboratory assessment of the human patch test hexanol gave responses significantly lower than the positive control and results were
similar between laboratories. N-hexanol was therefore not considered as a skin irritant.
Applicant's summary and conclusion
- Conclusions:
- In this inter-laboratory assessment of the human patch test hexanol gave responses significantly lower than the positive control and results were
similar between laboratories. N-hexanol was therefore not considered as a skin irritant.
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