Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
biotransformation and kinetics
Type of information:
other: Handbook data
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Handbook data lacking methodological details

Data source

Reference
Reference Type:
review article or handbook
Title:
Sodium azide.
Author:
Beste, C.E.
Year:
1983
Bibliographic source:
The Herbicide Handbook, 5th ed.: 438-41. The Weed Science Society of America, ISBN-13: 978-0911733013

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
no
Type of medium:
plant

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium azide
EC Number:
247-852-1
EC Name:
Sodium azide
Cas Number:
26628-22-8
Molecular formula:
N3Na
IUPAC Name:
sodium azide

Results and discussion

Transformation products:
yes
Identity of transformation productsopen allclose all
No.:
#1
Reference
Reference substance name:
Unnamed
IUPAC name:
hydrazoic acid
Identifier:
common name
Identity:
hydrazoic acid
No.:
#1
Reference
Reference substance name:
Unnamed
IUPAC name:
azide
Inventory number:
InventoryMultipleMappingImpl [inventoryEntryValue=EC 231-965-8]
CAS number:
7782-79-8
No.:
#2
Reference
Reference substance name:
Unnamed
IUPAC name:
nitrogen
Inventory number:
InventoryMultipleMappingImpl [inventoryEntryValue=EC 231-783-9]
CAS number:
7727-37-9
No.:
#3
Reference
Reference substance name:
Unnamed
IUPAC name:
dioxomethane
Inventory number:
InventoryMultipleMappingImpl [inventoryEntryValue=EC 204-696-9]
CAS number:
124-38-9

Applicant's summary and conclusion

Executive summary:

Sodium azide normally has a very short half life in plants. It is degraded by two paths - the azide ion can be oxidized by natural plant oxidizing agents such as nitrites, or hydrazoic acid could be formed by ion exchange and this can react with organic acids to form azides of these acids which then decompose by the Curtius rearrangement, followed by reaction of the resulting isocyanate with water releasing N2and CO2.