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Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Actions of sodium azide
Author:
Graham J.D.P.
Year:
1949
Bibliographic source:
Br J Pharmacol Chemother. 4(1):1-6, PMID: 18113147
Reference Type:
review article or handbook
Title:
Information profile sodium azide
Author:
Gregory A.R.
Year:
1978
Bibliographic source:
NIOSH / DCDSD

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
no
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium azide
EC Number:
247-852-1
EC Name:
Sodium azide
Cas Number:
26628-22-8
Molecular formula:
N3Na
IUPAC Name:
sodium azide

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 28 - < 34 mg/kg bw
Mortality:
no data
Clinical signs:
no data
Body weight:
no data
Gross pathology:
no data

Applicant's summary and conclusion

Conclusions:
In this study, the LD50 (mouse, i.p.) was reported to be 28-34 mg/kg bw.
Executive summary:

In an acute intraperitoneal toxicity study, mice were given a dose of sodium azide. The LD50 (mouse i.p.) was reported to be 28-34 mg/kg bw.