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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
21/02/2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test result performed using standard test guidelines
Qualifier:
according to
Guideline:
other: shake flask method
Principles of method if other than guideline:
The water solubility determination of test substance was done as per the shake flask method
GLP compliance:
no
Type of method:
flask method
Specific details on test material used for the study:
- Name of test material: (1,1-Dimethylethyl)-4-methoxyphenol
- Common name: Tert-butyl-4-methoxyphenol
- Molecular formula: C11H16O2
- Molecular weight: 181.2533 g/mol
- Smiles notation: [*]C(C)(C)C.COc1ccc(O)cc1
- InChI: 1S/C11H16O2/c1-11(2,3)9-7-8(13-4)5-6-10(9)12/h5-7,12H,1-4H3
- Substance type: Organic
- Physical state: Solid
- Physical Appearance: White to pale yellow solid with a waxy appearance
Key result
Water solubility:
610 mg/L
Conc. based on:
test mat.
Temp.:
29 °C
pH:
1.28
Remarks on result:
other: No other detail available

                                                                 TEST DESCRIPTION AND RESULT

Quantity of the Test Substance

(mg or ml)

 

Volume of water to be added

(mL)

Temperature at which the testing performed

(°C)

Procedures undertaken

Water solubility Value / Range

(in mg/L)

pH of test solution

 

 

100mg

 

 

100ml

 

 

29°C

Mechanical Stirring

24Hrs

 

 

610 mg/L

 

 

1.28

Membrane Filtration

Yes performed

 

Hot Air Oven Drying/

Air Drying

Performed at temperature of 500C

 

Conclusions:
The water solubility determination of test substance was done as per the shake flask method. The solubility was determine to be 610 mg/L at 29 0C. Thus the chemical is considered to be moderately soluble.
Executive summary:

The water solubility determination of test substance was done as per the shake flask method. The solubility was determine to be 610 mg/L at 29 0C. Thus the chemical is considered to be moderately soluble.

Description of key information

The water solubility determination of test substance was done as per the shake flask method. The solubility was determine to be 610 mg/L at 29 0C. Thus the chemical is considered to be moderately soluble.

Key value for chemical safety assessment

Water solubility:
610 mg/L
at the temperature of:
29 °C

Additional information

The water solubility determination of test substance was done as per the shake flask method. The solubility was determine to be 610 mg/L at 29 Deg C. Thus the chemical is considered to be moderately soluble.

From other reliable sources water solubility of test chemical is 213 mg/l at 25°C. This value indicates that the chemical is moderately soluble in water.