Registration Dossier

Administrative data

Endpoint:
dermal absorption
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 25013-16-5
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:- EPI Suite (DERMWIN) Various versions of EPI Suite dating back from 1990-2004.

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Modelling database
Principles of method if other than guideline:
EPI Suite (DERMWIN)
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): tert-butyl-4-methoxyphenol
- Substance type: Organic
- Physical state: Solid
Radiolabelling:
not specified

Test animals

Species:
other: no data
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified

Results and discussion

Percutaneous absorption
Remarks on result:
other: Dermal abs.: 0.00400 mg/cm2/event (LOW)

Applicant's summary and conclusion

Conclusions:
Dermal absorption of tert-butyl-4-methoxyphenol is low based on the value 0.00400 mg/cm2/event.
Executive summary:

According to Danish QSAR dermal absorption of tert-butyl-4-methoxyphenol is low based on the value 0.00400 mg/cm2/event.